Numerical and experimental modelling of the indentation of PVA-C soft tissue mimics
| Dublin Core | Elementos de metadatos de PKP | Metadatos para este documento | |
| 1. | Título | Título del documento | Numerical and experimental modelling of the indentation of PVA-C soft tissue mimics |
| 2. | ##rt.metadata.dublinCore.primaryAuthor## | ##rt.metadata.pkp.primaryAuthor## | Timothy Newson; Western University; Canadá |
| 2. | ##rt.metadata.dublinCore.primaryAuthor## | ##rt.metadata.pkp.primaryAuthor## | Mojdeh Zakeri; Western University; Canadá |
| 2. | ##rt.metadata.dublinCore.primaryAuthor## | ##rt.metadata.pkp.primaryAuthor## | Mansur Mulk; Western University; Canadá |
| 3. | Materia | Disciplina(s) | Ingeniería y desarrollo |
| 3. | Materia | Palabra(s) clave(s) | PVA cryogel; tissue-mimicking construct; stress-strain; finite element analysis; indenter |
| 4. | Descripción | Resumen | Creation of tissue-mimicking constructs is of great importance in the field of biomedical engineering. Polyvinyl Alcohol (PVA) is a biomaterial capable of simulating a wide range of geometries and mechanical properties of biological tissues. It is non-toxic, biocompatible, and easy to produce. PVA can be physically cross-linked by repeated cycles of freezing and thawing. The final product of this process is called PVA cryogel (PVA-C). The mechanical properties of PVA-C can be accurately controlled by changing PVA molecular weight, PVA concentration, and number and duration of freeze/thaw cycles (FTC). In this study, the stress-strain behavior of PVA cryogel was studied for different strain ranges using various laboratory tests (unconfined compression, uniaxial extension, cylindrical indentation and torsional vibration). The results of the experimental indentation work are reported with supporting finite element numerical modelling. This has provided greater understanding of the effects of sample boundary conditions on the observed results and provided calibrated hyperelastic constitutive relationships for the PVA-C materials used. Comparison of the mechanical behavior of PVA-C with other tests reported in the literature for a range of biological tissues suggest that the formulations of PVA-C investigated would be possible tissue mimics for a number of materials. |
| 5. | Editor/a | Agencia organizadora, ubicación | |
| 6. | Colaborador/a | Patrocinador(es) | |
| 7. | Fecha | (AAAA-MM-DD) | 2019-03-07 |
| 8. | Tipo | Estado & género | ##rt.metadata.pkp.peerReviewed## |
| 8. | Tipo | Tipo | |
| 9. | Formato | Formato de fichero | |
| 10. | Identificador | Indicador de Recursos Universal (URI) | https://eventos.uho.edu.cu/index.php/ccm/ccm9/paper/view/3142 |
| 11. | Fuente | Título de la revista/congreso; vol., núm. (año) | Conferencia Científica Internacional de la Universidad de Holguín; 9na Edición de la Conferencia Científica Internacional de la Universidad de Holguín |
| 12. | Idioma | Español=es | en |
| 13. | Relación | Ficheros adicionales | |
| 14. | Cobertura | Localización geo-espacial, periodo cronológico, ejemplo de investigación (género, edad, etc.) | |
| 15. | Derechos | Copyright y permisos | |